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Description

These agents are being evaluated in various clinical trials to determine their effectiveness in managing IPF through diverse mechanisms of action

Enhance neuronal survival: e.g., delivery of GDNF or neurturin genes

Placebo-corrected reductions in NITs at week 24 included 27% for MRI-PDFF (p=0.0005), 30% for ALT (p=0.0007), 27% for PRO-C3 (p 60K), Boston Pharmaceutical ( 8 kPa), genotyping for PNPLA3 and assessment of macro/microvascular complications