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Many of the tissue responses seen in acute inflammation, such as widening of blood vessels, increased permeability of capillaries and recruitment of immune cells, also occur in chronic inflammation

Cancer stem celldirected approaches include Hedgehog pathway inhibition, WNT/NOTCH targeting, metabolic disruption of oxidative phosphorylation, and antigen-specific strategies such as CD133-directed CAR-T cells (203, 204)

Banik A, Mondal J, Rakshit S, Ghosh K, Sha SP, Halder SK, Ghosh C, Mondal KC (2019) Amelioration of cold-induced gastric injury by a yeast probiotic isolated from traditional fermented foods