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Biochemical and biophysical research communications , 280 (1), 132138.

Healthy adults eating a balanced diet that includes animal products do not generally need to supplement B12. However, adds King, there are certain groups who can benefit from vitamin B12 supplementation, including: Adults over 50 , as B12 absorption naturally declines with age Those following a vegan diet , because B12 is almost exclusively found in animal foods People who are on long-term acid-blocking medications like PPIs or metformin, as well as anyone with absorption issues like celiac disease, Crohns, or post-bariatric surgery GLP-1 patients who arent getting enough B12 from food alone because the medications appetite suppression leads to lower food intake King explains, When deficiency is real, supplementation can effectively resolve the side effects of fatigue, brain fog, mood symptoms, and tingling in the hands and feet

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