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Another example of human bronchial epithelial cell line is represented by IB3-1 cells, derived from a CF patient carrying oneF508del allele and one W1282X nonsense mutation allele

Acknowledgments The work in Dr

To further strengthen the directionality of the integrative signal, we performed an additional enrichment analysis restricted to genes showing promoter-associated hypomethylation together with increased expression in RNA-seq

An example is the key observation that the thiol (-SH) group of the endogenous tripeptide glutathione can prevent cell damage caused by highly reactive chemical species, such as the toxic metabolite of paracetamol (see below and Fig