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The skeletal defects in the KO mice are caused, at least in part, by reduced proliferation, delayed differentiation and increased apoptosis in the growth plate (26)

When you inject synthetic HGH, you are adding a fixed amount of hormone to whatever your body is already producing

Head-to-Head Comparison Ipamorelin vs MK-677: Risks and Side Effects NEITHER OF THESE COMPOUNDS ARE FDA-APPROVED FOR ANTI-AGING OR PERFORMANCE ENHANCEMENT, and there is no head-to-head human trial comparing them directly