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Transcriptomic analysis revealed upregulated expression of the necroptotic (receptor-interacting protein kinase 3 (Ripk3), Ripk1, and mixed lineage kinase domain like pseudokinase (Mlkl)) and apoptotic (caspase-3 and caspase-8) machinery in epithelial cells from the ileum of mice at the onset of CIA [1]

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Considering the limitations and neglected gaps in current health-related approaches, this panel has proposed practical strategies that prioritize a holistic and integrated health perspective, specifically focusing on key elements of sustainable health behavior outlined in this report