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Glutamine mitigates oxidative stress-induced matrix degradation, ferroptosis, and pyroptosis in nucleus pulposus cells via deubiquitinating and stabilizing Nrf2

Baicalein, another important flavonoid, demonstrates significant cardioprotective effects through activation of the Nrf2 signaling pathway, thereby attenuating the oxidative stress damage caused by tert-butyl hydroperoxide in H9C2 cardiomyocytes

BZ conceived and designed the review, as well as wrote, reviewed, and edited the manuscript

Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis