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Mitocondrial dysfunction in human colorectal cancer progression

Absence of lot analytical characterisation : a contaminated or mis-dosed lot can invalidate an entire experimental series Preregistration and ARRIVE 2.0 Modern animal research standards require protocol preregistration (OSF, PreclinicalTrials.eu) with ex ante definition of primary, secondary criteria and exclusion rules

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Through integrative cross-disease and cross-species analysis, they identified a conserved set of cell states characteristic of early AD, termed the early cortical amyloid response