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There is a dearth of clinical data in humans, so any use should be cautious and supervised where legal

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However, a phase II clinical trial evaluating the effect of the DP2 receptor antagonist timapiprant in atopic dermatitis (NCT02002208) did not show any significant improvement [196] (Tables 7 and 8) PGD 2 , as well as its metabolite 15-d-PGJ 2 , when used in in vitro studies, inhibit the growth of human hair follicles explanted and hair growth in mice through the activation of the DP2 receptor [181]

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