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In practice, plasma samples are treated with strong reducing agents to break disulfide bonds, thus liberating free homocysteine and other small thiols such as cysteine and glutathione

Copper storage is mediated by the copper-binding protein metallothionein (MT), a reducing molecule rich in thiol groups with a high affinity for copper ions [21]

NF-B crosstalk with HIF-1 in PAECs In PAECs exposed to hypoxia, increased Cul-5 promotes NF-B activation by ubiquitinating TRAF6

ACS Sustain Chem Eng 6(2):21882196 Sun Y, Lin Y, Sun W, Han R, Luo C, Wang X, Wei Q (2019) A highly selective and sensitive detection of insulin with chemiluminescence biosensor based on aptamer and oligonucleotide-AuNPs functionalized nanosilica@graphene oxide aerogel