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Pyroglutamate selectively repleted glutamate, but not glutathione (Fig

In a randomized controlled trial that included 109 healthy men with mildly elevated cholesterol levels, 150 mg of aronia polyphenols daily for 90 days reduced total and LDL-cholesterol levels in men under 40 years of age, but not those 40 years and older, and had no effects on measures of glucose metabolism, blood pressure, oxidative stress, or inflammation

The most common side effects of GLP-1RAs include nausea, vomiting, diarrhea, and constipation, which are often of limited severity and tend to improve over time [24]