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Subjects from the placebo group did not show differences in total glutathione levels when comparing start with end of the study (medians, V2 = 824.4, V4 = 780 mg/L per % Ht, p -value = 0.734) (Figure 4B)

This review systematically integrates the critical role of glutamine metabolism in tumor development and therapeutic resistance, providing new perspectives and translational pathways for the development of precision therapeutic strategy selection based on metabolic plasticity modulation

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10.1016/j.phymed.2022.154164 20 MonteiroM.FarahA.PerroneD.TrugoL