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Unlike sequence-guided methods that rely on native viral motifs, this strategy typically employs heterologous pairssuch as the MS2 coat protein (MCP) or PP7 (PCP) systemswhere an aptamer hairpin is integrated into the target RNA while the ABP is genetically fused to the VLP structural protein (Gupta et al., 2024

doi: 10.4062/biomolther.2015.036 [DOI] [PMC free article] [PubMed] [Google Scholar] 165.Perrott KM, Wiley CD, Desprez P-Y, Campisi J

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