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Disclosure of interest: none Poster Session II - INTRACRANIAL HEMORRHAGE 02.00 - INTRACRANIAL HEMORRHAGE - 02.01 - INTRACEREBRAL HAEMORRHAGE P754 - ESOC25-1954 IMPACT OF PAIN AND ACUTE URINARY RETENTION ON BLOOD PRESSURE CONTROL IN ACUTE INTRACEREBRAL HAEMORRHAGE Luis Prats-Snchez 1 , Olalla Pancorbo 1 , Anna Ramos-Pachon 2 , Laura Llull 2 , Yolanda Silva 2 , Renato Simonetti 1 , Salvatore Rudilosso 3 , Laura Pardo 2 , Garbie Ezcurra 4 , lvaro Lambea-Gil 4 , Marina Guasch-Jimnez 4 , Pol Camps Renom 4 , David Rodriguez-Luna 1 1 Hospital Vall d'Hebron, Barcelona, Spain, 2 Hospital Universitari Dr Josep Trueta, Girona, Spain, 3 Hospital Clinic i Provincial de Barcelona, Barcelona, Spain, 4 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain Background and Aims: Care bundles for acute intracerebral haemorrhage (ICH), including early intensive blood pressure (BP) lowering, improve outcomes

Senescent Chondrocyte Removal & Chondrogenic Potential Restoration (PMC, 2021) FOXO4-DRI Removes Replication-Stress Senescent Chondrocytes in ACI Research Model A study published in PMC investigated FOXO4-DRI in the context of autologous chondrocyte implantation (ACI) a procedure in which in vitro chondrocyte expansion generates a senescent cell burden that adversely affects cartilage formation quality and quantity