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It is well known that -cells require redox signaling through cysteine modifications for efficient glucose-stimulated insulin secretion and insulin signaling because of their sensitive redox homeostasis

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Understanding the underlying cause is essential for determining the most appropriate treatment approach

Conclusions Our study highlights the capability of DMSO to induce changes in cellular processes in both cardiac and hepatic cells, but more severely, induce alterations in miRNA and epigenetic landscape in the 3D maturing cardiac model