CaCo-2 cells were received from ATCC (Cat# HTB-37)

Disclosure of interest: None Poster Session II - ACUTE ISCHEMIC STROKE MANAGEMENT 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.02 - ACUTE MANAGEMENT - Thrombolysis or thrombectomy P682 - ESOC25-1141 RISK OF SYMPTOMATIC INTRACRANIAL HEMORRHAGE IN ENDOVASCULAR STROKE TREATMENT: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS Joo Andr Sousa 1 , Sara Bernardo-Castro 2 , Joao Nuno Ramos 3 , Helena Donato 4 , Joo Sargento Freitas 1 1 Stroke Unit, Unidade Local de Sade de Coimbra, Portugal, Coimbra, Portugal, 2 IISPV Pere Virgili Health Research Institute, Tarragona, Spain, 3 Diagnostic Neuroradiology Unit, Imaging Department, Unidade Local de Sade Gaia e Espinho, Vila Nova de Gaia, Portugal, Vila Nova de Gaia, Portugal, 4 Documentation and Scientific Information Service, Hospitais da Universidade de Coimbra, Unidade Local de Sade de Coimbra, Portugal, Coimbra, Portugal Background and Aims: Symptomatic intracranial hemorrhage (sICH) is a key safety outcome in endovascular therapy (EVT) for acute ischemic stroke (AIS)

As treatment duration was not recorded, residual confounding cannot be fully excluded
Reduced carbohydrate tolerance, increased requirement for insulin and oral hypoglycemic drugs in diabetic patients