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To restore antioxidant capacity, the reduced form of coenzyme Q 10 , ubiquinol (CoQ 10 H 2 ), regenerates -TOH by donating electrons, producing either the semiquinone radical (CoQ 10 H) or the fully oxidized form, ubiquinone (CoQ 10 )

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Importantly, MP-13 did not induce psychological dependence (confirmed by conditioned place preference tests) nor affect gastrointestinal motilityan advantage over classic opioid agonists