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VEGF-A is known to promote the retinal expression of ICAM-1, promoting the adhesion of leukocytes to the retinal vessels, the disintegration of the bloodretina barrier, ECs damage, and apoptosis [184]

A clear relationship between the severity and incidence of lesions and the amount of T-2 toxin was also demonstrated by Chi et al

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In contrast, murine studies show that while the total number of peripheral B cells in mice remains consistent as they age, the influx of new nave B cells into peripheral tissues decreases in older mice