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Since tirzepatide may slow gastric emptying as part of its mechanism of action, patients with pre-existing severe gastroparesis could experience worsening of symptoms, including nausea, vomiting, and potential complications related to delayed gastric emptying

Digestive disorders: Vitamin B12 absorption can be impaired by digestive conditions like Celiac disease and Crohns disease

Our published-research FAQs recommend keeping a dedicated spreadsheet of vial usage so that reviewers can trace any observed variability back to material handling rather than biology

[3] [6] If no reversible cause is found, or when found it cannot be eliminated, lifelong vitamin B 12 administration is usually recommended