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Restoring DLX-mediated GABAergic neuron differentiation or enhancing GABA signaling (e.g., via GABAA receptor agonists) could potentially rescue circuit imbalances in DLX-related ASD subtypes

4j): In the first step, lactate oxidation drives the reduction of NAD+ bound to LDHB and CoQ, resulting in the release of pyruvate, generating NADH/PQQ bound to LDHB

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