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Description

Frith C

Cochlear function was assessed by pre- and post-noise (after 168 hours) recordings of distortion product otoacoustic emissions (DPOAEs) and auditory brainstem responses (ABR)

-glutamyl-cysteine synthetase is elevated by Nrf2-ARE pathway for glutathione (GSH) synthesis (Arredondo et al., 2010) (Figure 2)

the aqueous solution of GSH is further concentrated by nanofiltration/reverse osmosis and/or evaporation under vacuum, after which the product is isolated in solid form, precipitating it by adding ethanol or another water-miscible organic solvent