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In further asepcts, the invention provides methods of reversing, ameliorating or slowing progression of at least one symptom of Lewy body pathology in a patient in need thereof

Following 72 h of dialysis, the resulting solution was by using low-temperature freeze dryers, which yielded P4 (301 mg), presented as a brown powder

Slides were fixed with 4% paraformaldehyde in PBS for 10 min, washed three times in PBS, permeabilized using a 1:1,000 dilution of Triton X-100 in casein solution, washed another three times in PBS and then blocked for 30 min with casein solution (Thermo Fisher)