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TABLE 2 Concentrations of constituents and metabolites determined after single (S) or multiple (M) intake of Pycnogenol by human volunteers (70) or patients ( *Pilot investigation with one participant

Drug Metab Rev 47:175190 Graham JO, Agbenorhevi JK, Kpodo FM (2017) Total phenol content and antioxidant activity of okra seeds from different genotypes

doi:10.1155/2013/424163 [17] Wojciechowska A, Osowski A, Jwik M, Grecki R, Rynkiewicz A, Wojtkiewicz J

Naringenin (Nar), a bioactive flavanone compound, activates the AMPK/SIRT1 signalling pathway, restoring mitochondrial Ca 2+ and decreasing ROS production as well as upregulating eNOSactivity, increasing NO production, and improving ED (Li et al., 2021)