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Additionally, TMAO induces oxidative stress and activates NLRP3 inflammasomes through the MAPK pathway, thereby impairing renal function and inducing renal fibrosis (Andrikopoulos et al., 2023)

Moreover, thanks to the content of compounds that have antioxidant properties, the peanut butter can contribute to the neutralization of free radicals and reactive oxygen species and also to reduce oxidative stress and delay aging processes

In the setting of hyperlipidemia, conspicuous reduction in GSH content in the liver was observed, which was accompanied by the reduction in the concentration of cysteine-the rate limiting precursor of GSH, suggesting that reduced availability of cysteine led to impaired GSH production, and subsequent decreased GSH pool size