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Gene-Environment Interactions in Inflammatory Bowel Disease: A Systematic Review of Human Epidemiologic Studies

Most intracellular zinc is tightly bound to metalloproteins and metalloenzymes, where it serves structural and catalytic roles

Quinlan et al., 2013), complex I and complex III (Venditti et al., 2013) have been shown to be the most important sources of mitochondrial superoxide generation, although significant production of ROS in complex II has recently also been reported (Quinlan et al., 2012)

[90] validated circulating FABP2 and IL-6 mRNA as reliable noninvasive biomarkers reflecting intestinal epithelial injury and barrier dysfunction in both clinical (30 human neonate sample) and experimental models (in SPF BALB/c mice)