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Arch Neurol Psychiatry

As for early breast cancer, Combining PARP inhibitors and standard chemotherapeutic agents in the treatment of cancer could be challenging due to toxicities

Start conservatively, track progress, adjust based on results

Sites of production of reactive oxygen species ROS are normally produced in all cellular compartments, plastids (chloroplasts in aerial parts), mitochondria, peroxisomes/glyoxysomes, cytosol, plasma membrane, apoplast (cell wall) (Figure 4)