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(2019) and Chen et al

2 HIV infection leads to a deficiency in CD4+ T cells and eventual loss of immunity, causing increased susceptibility to opportunistic pathogens

(50 mg IM twice weekly slowed functional decline by ~43% in early-stage ALS.) Clinical safety of ultra-high-dose methylcobalamin in patients with amyotrophic lateral sclerosis: Open-label extension (long-term safety data)