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miR-141/200c repress SIRT1 and thereby blunt PGC-1 deacetylation/activation, attenuating mitochondrial biogenesis and antioxidant support programs (8184)

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Research published in Redox Biology found that when cells were exposed to stress, older cells' glutathione levels plummeted to just 10% of their original levels, while younger cells maintained at least 35% of their glutathione