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Consequently, therapeutic strategies aimed at restoring proteostasis have emerged as central disease-modifying approaches

Fourth, the delayed release and sublingual formulations specifically address the degradation problem

Also, substituents on the C-5 position in the quinoline ring play a crucial role, not only in the phototoxicity but also the photostability of the fluoroquinolones [179] suggesting that some fluoroquinolones are more resistant than others to photodegradation and hence would have a longer residence time in skin cells (Fig

age at the time of first LSM and stable high LSM turned out to be the independent risk factors for HCC