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Graphical Abstract Access this article Similar content being viewed by others Data availability All data and materials related to this study are available from the corresponding author on reasonable request

Drug administration protocols (dose, timing, and route) are detailed in the Pharmacological Interventions section

The amount of methylated DNA is proportional to the OD intensity measured, which can be calculated with the kit's included formulas for relative methylation status of two different DNA samples or absolute quantification of 5-methylcytosine (5mC) using a standard curve