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Currently, there is an increasing focus on therapeutic strategies targeting the side branches of glycolysis, especially the serine/glycine (ser/gly) synthesis pathway, since it is upregulated in approximately 30% of all cancers, including GBM [21]

Over the past decade, the number of patients with ORN has doubled

By contrast, PET imaging with TSPO ligands can visualize molecular inflammation in vivo

Carrier-Mediated Transport (CMT) CMT of small molecules across the BBB occurs after the interaction between a substrate compound and the specific transport protein, which can be expressed in either the luminal or abluminal membrane or both sides of the brain capillary endothelial cells (Table I)