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Eur J Clin Pharmacol 65(12):12111228 FDA Drug Safety Communication (2013) FDA approves new label changes and dosing for zolpidem products and a recommendation to avoid driving the day after using Ambien CR [press release]

(PubMed) Zhang CL, Zeng T, Zhao XL, Yu LH, Zhu ZP, Xie KQ

In the hot-plate test, pretreatment with idazoxan (10 g) was able to reverse the antinociceptive action of mitragynine (10 g, i.c.v.) in mice ( i values in the low micromolar range (1.39.29 M)