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Description

Under the induction of artesunate, the level of lipid peroxidation in hepatocellular carcinoma (SMMC-7721) cells increases, and the use of iron-chelating agent deferoxamine can eliminate the accumulation of intracellular lipids caused by artesunate peroxidation [175, 176]

In modeling, three templates such as 2F8A:A ( GPX1, GPX3, GPX6 , and GPX7 ), 2V1M:A ( GPX2 and GPX5 ), and 2P5Q:A ( GPX4 and GPX8 ) were used to maximize the alignment coverage, percentage identity and confidence for submitted sequences