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Interestingly, loss of muscle mass in itself appears not to be associated with functional decline and disability [51] but rather maintenance of muscle strength is key to preventing functional decline [52], with randomised controlled trials (RCTs) demonstrating the benefit of resistance training in older adults [53]

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Type-I IFN: Type-I IFN facilitates dendritic cell (DC) maturation, enhances autoimmune T cell survival, and activates autoantibody-producing B cells, primarily through sustained IFN- production, autophosphorylation, and activation of the IFN- receptor (IFNAR)-associated Janus kinases (JAKs) and signal transducers and activators of transcription (STATs) (87, 88)

Unlike conventional foods, functional foods are enriched with certain bioactive ingredients, either naturally present in the food or added through fortification