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LC3 expression depends, among others, on the activity of SIRT1, transcription factor EB (TFEB), histone acetyltransferase (HAT) and p300 HAT (EP300)

An even lower TUL for iodine has been proposed by the American Thyroid Association (ATA), that advises against exceeding 500 g per day of iodine, particularly in children, the elderly and during pregnancy [22]

In 1977, an expert panel convened by the FDA issued urgently worded advice, saying it was obligatory to put a warning on the drugs label that it could cause severe liver damage. After much debate, the FDA added the warning 32 years later

The working solution in the BCA protein concentration determination kit (P0012, Beyotime, China) was used to measure the absorbance of the sample at 562 wavelengths, and the sample concentration was calculated based on the standard curve