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Legrain understood the principals and aesthetics of both modern and African art to a degree that most other designers of the period did not-- perhaps the result of spending considerable time with his patron, the couturier Jacques Doucet, and his collection (which included Picasso's masterpiece Les Demoiselles d'Avignon, several important Cubist works, and a group of African sculptures)

Studies have shown that glucose production, clearance, oxidation, and glycolysis rates are increased in patients with COPD compared to healthy subjects [108]

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