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Abstract The leptomeninges present a challenging tumour microenvironment with cells receiving low levels of nutrients and oxygen from cerebrospinal fluid (CSF), however these metabolic constraints are yet to be exploited therapeutically

However, there has been no comprehensive summary or discussion of this topic in the literature

In this review, the biochemical basis of oxidative stress in ASD is examined, the mechanistic understanding of antioxidant-based interventions is assessed, and the structureactivity relationships that dictate their therapeutic value are discussed

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Abdel Latef A.A.H., Tran L.-S.P