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QJM :hcaf037

Thus, the enzyme catalyzes the hydroxylation of the substrate, forming a superoxide radical that decarboxylates 2-OG, forming a ferryl intermediate, which helps to bring iron to its active state (Fe 2+ )

Several types of inflammasomes, including the Node-like receptor protein family (e.g., NLRP1, NLRP3, NLRP6, NLRP12, NLRC4) interact with gut microbiota to maintain gut homeostasis, as illustrated in section 5 below