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If you want to join a community of genuinely curious people operating at the frontier of bio-optimization, come find out why StayCurious Metabolism is one of the top best-selling science newsletters on Substack.

GABAergic interneurons in epilepsy: more than a simple change in inhibition

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Our experiments have elucidated a coordinated mechanism underlying this phenomenon, characterized by the rapid induction of ISR and oxidative stress response (OSR), accompanied by increased GDF15 and FGF21, and a reduction in CoA levels resulting in metabolic inefficiency, therefore offering insights for potential intervention in metabolic diseases and body-weight control