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Given the more direct drug delivery route, intranasally delivered drugs have the potential to be more potent, work more quickly, be better targeted, produce less side effects and be more effective overall

Similarly, to enhance the efficacy of chain-breaking antioxidants, new derivatives with reduced toxicity and improved effectiveness, such as novel synthetic variants, various conjugates, or nanoformulations, specifically targeted to active sites of oxidative stress and particular ROS need to be developed

Having assessed a patient we may have concluded that the issue is either in the subacromial space, glenohumeral joint or AC joint

In addition, the derivatives of various plant metabolites can target the GSH/GPX4 pathway and induce ferroptosis