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Gupta S, Pablo AM, X c J et al (1997) IFN-gamma potentiates atherosclerosis in ApoE knock-out mice

The side-effect arc, in felt terms Nausea is front-loaded

While this trial showed trends toward fat loss in the treatment groups, the primary endpoint of statistically significant weight reduction compared to placebo was not consistently achieved across all dose groups, and effect sizes were more modest than hoped