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The shortcomings of anti-VEGF or anti-VEGF receptor antibodies and tyrosine kinase inhibitors, having some drawbacks including inappropriate pharmacokinetics (Abs) and low specificity (TKIs), have limited their clinical outcomes 10,11

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The most common side effects of GLP-1RAs include nausea, vomiting, diarrhea, and constipation, which are often of limited severity and tend to improve over time [24]

For those with chronic conditions like IBD or EPI, ongoing management of the underlying disease is necessary, and periodic B12 monitoring may be recommended to ensure levels remain adequate