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Transmission of NLRP3-IL-1beta signals in cerebral ischemia and reperfusion injury: from microglia to adjacent neuron and endothelial cells via IL-1beta/IL-1R1/TRAF6

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While earlier studies were limited by crude exposure assessments and lack of chronobiological context (e.g., individual chronotype, sleep quality), newer cohorts are integrating objective measurements such as actigraphy, light sensors, and sleep diaries 28

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