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Several studies have reported that chlorogenic acids found in coffee are greatly associated with a decreased risk of diabetes, Parkinson's, Alzheimer's Disease, and even liver cancer (Komes & Busic, 2014)

The medullary thyroid carcinoma signal observed in rodent studies at supratherapeutic doses has not been confirmed in human populations across approximately eight years of post-market surveillance, but the contraindication in patients with relevant personal or family history remains appropriate

While most people obtain B-12 from meat, eggs, and dairy, excessive intake from food and supplements has no adverse effects in healthy individuals

Sun, H., Saeedi, P., Karuranga, S., GBD 2021 Diabetes Collaborators