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Commonly used target detection methods such as immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) are subject to inter-laboratory variability, ambiguous cutoff definitions, and limited quantitative precision [304, 305]

5-in-1 Practitioner Formula: Quercetin, NAC, Reishi Mushroom, Bromelain, and Stinging Nettle support immune balance, cellular defense, and healthy histamine response

To address these challenges, emerging strategies such as nanoencapsulation and advanced delivery systems have been developed to enhance bioavailability and improve targeting mechanisms [28, 94, 216]