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Description

Proviral insertion in Murine lymphomas (PIM2), a serine/threonine kinase and a proto-oncogene [104], phosphorylates hexokinase II (HKII), which results in increased enzyme stability and activity [105]

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Betibeglogene autotemcel is an autologous hematopoietic stem cell-based gene therapy that may increase functional adult HbA and total Hb to normal levels and eliminate dependence on regular packed red blood cell transfusions (185)

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