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At the end of the open-label extension study after 36 weeks, patients treated with resmetirom had improvements in proton density fat fraction, reduction of lipoprotein (LDL cholesterol, ApoB, triglycerides, and ApoC3), reduction of liver enzymes, and increased sex hormonebinding globulin from baseline

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-Methyltryptophan (-MT), a pharmacological inhibitor of SLC6A14, can inhibit the proliferation of cancer cells in vitro and tumor growth in vivo (Karunakaran et al., 2011

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