bso inhibition glutathione of synthesis and recycling decreases BSO is an inhibitor of

Selenium supplementation could increase GPX4 expression in T cells, thereby leading to an increase in Tfh cell numbers and improved antibody responses in vaccinated mice and young adults post-influenza vaccination (97)

When selenium is reduced, some selenoproteins in the body quickly disappear (low grades), while others can continue to be synthesized even when selenium levels are reduced (high grades) (Banning et al., 2008b)

doi: 10.1093/oxfordjournals.schbul.a007142 21 DoKQTrabesingerAHKirsten-KrgerMLauerCJDydakUHellDet al

17 Various epithelial cells, such as enterocytes, alveolar cells, renal proximal tubular cells, endothelial cells, and retinal pigmented epithelial cells, are capable of exogenous GSH uptake, which supports the function of GSH-dependent detoxification systems