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Mitochondrial DNA (mtDNA) depletion and mutations in certain mitochondrial genes are linked to reduced insulin secretion and increased oxidative stress, although studies on the exact mechanisms are scarce ( 2.4.1 Basic science research Similarly, in the context of PD, mitochondrial dysfunction can drive neurodegeneration

Most patients are sadly more resistant to subsequent therapies and have a recurrence of the disease (170)

Our results demonstrated that CS exposure led to an enhancement of oxidative stress reflected by increased MDA level, associated with diminished expression of Nrf2, GSH and T-AOC activity in the lung tissues

Pregnant ya breastfeeding individuals, immunosuppressant medication lene wale, ya liver, kidney, ya autoimmune conditions wale logon ko shuru karne se pehle doctor consult karna chahiye