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However, some people struggle to absorb the vitamin B12 that they take in through their diets

M9a + sh EPAS1 cells upregulate HIF-1-BNIP3/NIX-mediated mitophagy and suppress mtDNA-mediated inflammation under hypoxia condition Hypoxia-induced mitophagy is typically mediated by BNIP3/NIX and regulated by HIF-1 [28], so we first excluded the involvement of PINK1/PARKIN-mediated mitophagy in Tibetan hypoxia adaptation (Supplementary Fig

Specifically, polymorphisms in ethanol-metabolizing genes like ADH1B and ALDH2 are closely linked to oxidative stress, DNA damage, and inflammatory responses induced by alcohol consumption

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